Creative Biolabs

Mouse Anti-beta-synuclein Monoclonal Antibody (AB071), Unconjugated

[CAT#: NAB2007FY1537]

Mouse Monoclonal to beta-synuclein

Host Species:
Mouse
Species Reactivity:
Human; Rat; Mouse; Cow; Porcine
Applications:
WB; IF; IHC

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Description
β-synuclein is a member of the synuclein family. The other two members are α-synuclein and γ-synuclein. Each protein is encoded by a different but related gene. α-synuclein was originally isolated from the electrical organs of torpedoes (1) as the main synaptic vesicle-associated protein, and direct homologs of α-synuclein have been found in all vertebrates. Later work linked the expression of α-synuclein to several human brain pathologies, so it is the main component of Lewy bodies in Parkinson's disease (2-5). β-synuclein is isolated as a component of the brain of normal and diseased patients, as a protein that is clearly related to α-synuclein but is different (6). The size of the human β-synuclein molecule is 134 amino acids, while the α-synuclein is 140 amino acids, and the N-terminal half of the two molecules are almost the same, while the C-terminal region varies more.
Immunogen
C-terminal peptide of human β-synuclein EPEGESYEDPPQEEYQEYEPEA coupled to KLH
Species Reactivity
Human; Rat; Mouse; Cow; Porcine
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1
Clone Number
AB071
Applications
WB; IF; IHC
Application Notes
WB:1:1,000 IF/ICC: 1:500-1,000
Form
Liquid
Formulation
50% PBS, 50% glycerol
Preservatives
5mM NaN3
Concentration
1 mg/ml
Shipping
Gel Pack
Storage
Store at 4°C for short term, for longer term at -20°C
Handling Advice
The antibody solution should be gently mixed before use.
Research Use Only
For research use only
Target
Beta Synuclein
Official Name
SNCB
Full Name
beta Synuclein
Alternative Names
SNCB; entrez:6620; synuclein beta
Gene ID
6620 (Human); 104069 (Mouse); 113893 (Rat)
Uniprot ID
Q16143 (Human); Q91ZZ3 (Mouse); Q 63754 (Rat)
For Research Use Only. Not For Clinical Use.
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