Product
NeuroMab™ Mouse Anti-Galectin-3 Binding Protein Monoclonal Antibody (CBP1936)
[CAT#: NAB2007FY378]
Mouse Monoclonal [2B1] to Galectin-3 Binding Protein
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Mouse anti-human galectin-3 binding protein antibody can recognize galectin-3 binding protein, also known as L3 antigen, MAC2BP, Mac-2-binding protein, basement membrane autoantigen p105, lectin and galactoside binding soluble 3- Binding protein, mac -2 BP, serum protein 90K, transport and Golgi tissue 10 homolog B and tumor-associated antigen 90K.
Galectins are a family of β-galactoside-binding proteins, which are involved in regulating cell-cell and cell-matrix interactions. Galectin-3 binding protein has been found to be elevated in the serum of cancer patients and in the serum of patients infected with human immunodeficiency virus (HIV). It seems to be related to the immune response related to the cytotoxicity of natural killer (NK) and lymphokine activated killer (LAK) cells. Using fluorescence in situ hybridization, the full-length 90K cDNA has been mapped to chromosome 17q25. The natural protein specifically binds to a lectin associated with human macrophages called Mac-2, and also binds to galectin-1 (provided by RefSeq, July 2008).
The mouse anti-human galectin-3 binding protein antibody can detect a band of 75 kDa. The antibody has been extensively validated by Western blot using whole cell lysates.
Galectins are a family of β-galactoside-binding proteins, which are involved in regulating cell-cell and cell-matrix interactions. Galectin-3 binding protein has been found to be elevated in the serum of cancer patients and in the serum of patients infected with human immunodeficiency virus (HIV). It seems to be related to the immune response related to the cytotoxicity of natural killer (NK) and lymphokine activated killer (LAK) cells. Using fluorescence in situ hybridization, the full-length 90K cDNA has been mapped to chromosome 17q25. The natural protein specifically binds to a lectin associated with human macrophages called Mac-2, and also binds to galectin-1 (provided by RefSeq, July 2008).
The mouse anti-human galectin-3 binding protein antibody can detect a band of 75 kDa. The antibody has been extensively validated by Western blot using whole cell lysates.
Immunogen
A recombinant protein corresponding to amino acids 19-300 of human galectin 3 binding protein (NP_005558) produced in E. coli
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1
Clone Number
CBP1936
Applications
WB
Application Notes
WB (1/1000)
Relevant Diseases
Lou Gehring's Disease
Research Areas
Neuroregeneration
Conjugation
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1573
Product Properties
Form
Liquid
Formulation
PBS; 0.09% Sodium Azide
1% Bovine Serum Albumin
50% Glycerol
1% Bovine Serum Albumin
50% Glycerol
Preservatives
Yes
Purification
Affinity chromatography from tissue culture supernatant.
Endotoxin Level
Low Endotoxin
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Publications
Publications (0)
For Research Use Only. Not For Clinical Use.
