Armenian Hamster Anti-Mouse CD40 Monoclonal Antibody (CBP3664)
[CAT#: NAB2012483LS]
Anti-CD40 Monoclonal Antibody [FITC]
- Host Species:
- Armenian Hamster
- Species Reactivity:
- Mouse
- Applications:
- FC
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
CD40 is a 48 kD type I transmembrane glycoprotein, also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily, expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39) expressed on activated T cells, is important in costimulation and immune regulation. The HM40-3 antibody has been reported to stimulate dendritic and B cell proliferation and block CD40-CD40L interactions.
Immunogen
(BALB/c x NZB)F1 mouse-derived lymphoma WEHI 231
Species Reactivity
Mouse
Clonality
Monoclonal
Host Species
Armenian Hamster
Isotype
IgM
Clone Number
CBP3664
Applications
FC
Application Notes
FCM (≤ 1.0 µg per million cells in 100 µL volume)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation; Neurodegeneration
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA.
Concentration
1.0 mg/mL
Purification
Affinity Chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Target
CD40
Official Name
CD40
Full Name
Cluster of differentiation 40
Alternative Names
PTPRC; B220; CD45; CD45R; GP180; L-CA; LCA; LY5; T200; protein tyrosine phosphatase; receptor type C; protein tyrosine phosphatase receptor type C
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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