Mouse Anti-Human PLAP Monoclonal Antibody (CBP3683)
[CAT#: NAB201215LS]
Anti-PLAP Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- IHC-P; WB
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
PLAP is a membrane-bound glycosylated dimeric enzyme that was initially identified in the placenta. PLAP is also known as phospholipase A2 activating protein. Abnormal amyloid beta-induced activation of synaptic phospholipase A2 results in synaptic degeneration due to elevated levels of platelet-activating factor, suggesting that PLAP may be a contributing factor in synaptic damage observed in Alzheimer's disease patients. Clinically, PLAP is broadly used as a tumor marker, especially in geminoma, seminoma, and ovarian cancer.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1, κ
Clone Number
CBP3683
Applications
IHC-P; WB
Application Notes
IHC (2.0-10 µg/ml); WB (0.5-10 µg/mL)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation; Neurodegeneration
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide.
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Publications
Publications (0)
For Research Use Only. Not For Clinical Use.
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