Product
Mouse Anti-Human Rab7 Monoclonal Antibody (CBP3737)
[CAT#: NAB2012101LS]
Anti-Rab7 Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- IHC-P; WB
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Alzheimer's disease is characterized by the accumulation of aggregated Aβ peptides in senile plaques and vascular deposits. Aβ peptides are derived from amyloid precursor proteins (APP) through sequential proteolytic cleavage of APP by β-secretases and γ-secretases generating diverse Aβ species. Aβ can aggregate to form soluble oligomeric species and insoluble fibrillar or amorphous assemblies. Some forms of the aggregated peptides are toxic to neurons.
Immunogen
Human amyloid beta fibrils
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG2b, κ
Clone Number
CBP3737
Applications
IHC-P; WB
Application Notes
IHC-P (0.5-10 µg/mL); WB (2.0-10 µg/mL)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation; Neurodegeneration
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide.
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
References
1. Kumar A, et al. 2015. Pharmacol Rep. 67(2):195.
2. Sadigh-Eteghad S, et al. 2015. Med Princ Pract. 24(1):1
3. Hampel H, et al. 2015. Expert Rev Neurother. 15(1):83.
4. Puig KL & Combs CK. 2012. Exp Gerontol. 48(7): 608.
5. Selkoe DJ & Hardy J. 2016. EMBO Mol Med. 8(6):595.
6. Walsh DM, et al. 2007. J Neurochem. 101(5):1172.
2. Sadigh-Eteghad S, et al. 2015. Med Princ Pract. 24(1):1
3. Hampel H, et al. 2015. Expert Rev Neurother. 15(1):83.
4. Puig KL & Combs CK. 2012. Exp Gerontol. 48(7): 608.
5. Selkoe DJ & Hardy J. 2016. EMBO Mol Med. 8(6):595.
6. Walsh DM, et al. 2007. J Neurochem. 101(5):1172.
Publications
Publications (0)
Neural Antibodies
Neural Cell Lines
For Research Use Only. Not For Clinical Use.
