Product
Mouse Anti-Human ALDH1A1 Monoclonal Antibody (CBP3877)
[CAT#: NAB2012435LS]
Anti-ALDH1A1 Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB; IHC-P; ICC
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
ALDH1A1 belongs to the aldehyde dehydrogenase family of proteins and is involved in the metabolism of alcohol. Alcohol metabolism involves two main liver isoforms, mitochondria and cystic. ALDH1A1 is also involved in retinol metabolism, where retinol is converted to retinoic acid. It is suggested that the differentiation of hematopoietic stem cells is mediated by ALDH1A1 controlling the retinoid signal pathway.
Immunogen
Clone M562 was generated from a recombinant protein corresponding to amino acids in the N-terminal region from human ALDH1A1.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG2a, κ
Clone Number
CBP3877
Applications
WB; IHC-P; ICC
Application Notes
WB (1.0-5.0 µg/mL); IHC-P (1.0-5.0 µg/mL); IHC (2.0-10.0 µg/mL)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation; Neurodegeneration
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide.
Concentration
1.0 mg/mL
Purification
Affinity Chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Target
ALDH1A1
Official Name
ALDH1A1
Full Name
Aldehyde Dehydrogenase 1 Family Member A1
Alternative Names
Aldehyde Dehydrogenase 1 Family Member A1; Retinaldehyde Dehydrogenase 1; EC 1.2.1.36; RALDH 1; ALDH-E1; RALDH1; ALHDII; ALDH1; PUMB1; ALDC; Epididymis Secretory Sperm Binding Protein Li 53e; Aldehyde Dehydrogenase 1 Family; Member A1; Aldehyde Dehydrogenase Family 1 Member A1; Aldehyde Dehydrogenase; Liver Cytosolic;
Uniprot ID
P00352 (Human); P24549 Mouse (Mouse)
References
1. Xu SL, et al. Am J Cancer Res. 2015 Mar 15;5(4):1471-83.
2. Olmez I, et al. J Cell Mol Med. 2015 Jun;19(6):1262-72.
3. Schäfer A, et al. Neuro Oncol. 2012 Dec;14(12):1452-64.
4. Adam SA, et al. Brain Pathol. 2012 Nov;22(6):788-97.
2. Olmez I, et al. J Cell Mol Med. 2015 Jun;19(6):1262-72.
3. Schäfer A, et al. Neuro Oncol. 2012 Dec;14(12):1452-64.
4. Adam SA, et al. Brain Pathol. 2012 Nov;22(6):788-97.
Publications
Publications (0)
Neural Antibodies
Kits
For Research Use Only. Not For Clinical Use.
