Product
Mouse Anti-Human PAR-2 Monoclonal Antibody (CBP3964)
[CAT#: NAB2012895LS]
Anti-PAR-2 Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- IHC-P; WB
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Proteinase-activated receptor 2 (PAR-2), also known as G-protein coupled receptor 1 or thrombin receptor-like 1, is a receptor for trypsin and trypsin-like enzymes coupled to G proteins. The function of PAR-2 is mediated through the activation of multiple signaling pathways, including MAPK, phospholipase C, intracellular calcium, and I-kappaB kinase/NF-kappaB and Rho. PAR-2 is also involved in the regulation of innate and adaptive immunity, the modulation of inflammatory responses, and as a sensor of proteolytic enzymes generated during the course of infection.
Immunogen
Human PAR-2 protein and was mapped to amino acids 37-50.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG2a
Clone Number
CBP3964
Applications
IHC-P; WB
Application Notes
IHC-P (10 µg/mL); WB (0.5-1.0 µg/mL)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation; Neurodegeneration
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA.
Concentration
1.0 mg/mL
Purification
Affinity Chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Publications
Publications (0)
For Research Use Only. Not For Clinical Use.
