Mouse Anti-Human HDAC7 Monoclonal Antibody (CBP3994)
[CAT#: NAB2012992LS]
Anti-HDAC7 Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- IP; IHC-P; WB
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
HDAC7 is a class IIa histone deacetylase and its enzymatic activity is dependent on the interaction with HDAC3. HDAC7 is highly expressed in CD4+CD8+ double-positive thymocytes and has been suggested to repress the expression of Nur77 through the transcription factor MEF2D. HDAC7 is mostly localized to the nucleus and can be sequestrated in the cytoplasm by interacting with 14-3-3 protein during T cell receptor activation.
Immunogen
Synthetic HDAC7 peptide conjugated to KLH (1-17 a.a.)
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1, κ
Clone Number
CBP3994
Applications
IP; IHC-P; WB
Application Notes
IP (1:50-1:100); WB (0.5-2.5 µg/mL)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation; Neurodegeneration
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide.
Concentration
1.0 mg/mL
Purification
Affinity Chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Publications
Publications (0)
For Research Use Only. Not For Clinical Use.
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