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Creative Biolabs

Anti-GRK (CBP4006)

[CAT#: NAB20121015LS]

Anti-GRK (pan-reactive) Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Human; Rat
Applications:
WB; IHC-P

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Product Overview

Description

G protein-coupled receptor kinases (GRK or GPCRK) desensitize G protein-coupled receptors (GPCR) by phosphorylating their intracellular domains after G protein activation. GRKs are known to also regulate GPCRs through phosphorylation-independent mechanisms.

Immunogen

G protein-coupled receptor kinases (GRK or GPCRK) desensitize G protein-coupled receptors (GPCR) by phosphorylating their intracellular domains after G protein activation. GRKs are known to also regulate GPCRs through phosphorylation-independent mechanisms.

Species Reactivity

Human; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP4006

Applications

WB; IHC-P

Application Notes

WB (2.0-10 µg/mL); IHC-P (5.0-10.0 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

1.0 mg/mL

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

GPCRK

Official Name

GPCRK

Full Name

G protein-coupled receptor kinase

Alternative Names

GRK1; ADRBK1; ADRBK2; GRK4; GRK5; GRK6; GRK7; G protein-coupled receptor kinase; GRKs
Publications

Publications (0)

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