Mouse Anti-Human Haptoglobin Monoclonal Antibody (CBP4266)

[CAT#: NAB210136LS]

Anti-Haptoglobin Monoclonal Antibody

Host Species:: Mouse

Species Reactivity:: Human

Applications:: WB

Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Request Pricing

Inquiry

Product Overview

Description

Haptoglobin is a protein that is mainly expressed by hepatic cells in the liver. Haptoglobin is an acute-phase antioxidant that binds to free hemoglobin (Hb) in the plasma and inhibits the oxidative activity of hemoglobin. Individuals carrying the haptoglobin 2-2 genotype have decreased affinity to Hb and are at a higher risk of developing cerebral aneurysm-related complications due to impaired anti-inflammatory pathways. This highlights haptoglobin as part of the Hb scavenging mechanism, which may be critical for clearing Hb after intracranial bleeding and neuroprotection.

Immunogen

Recombinant human Haptoglobin corresponding to amino acids 168 - 391 expressed by E.coli.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP4266

Applications

Application Notes

WB (1-5 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

0.01 M PBS, pH 7.4, containing 0.02% NaN3, 50% glycerol.

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Handling Advice

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.