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Creative Biolabs

Mouse Anti-Rat CD229 Monoclonal Antibody (CBP4385)

[CAT#: NAB2101178LS]

Anti-CD229 Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Rat
Applications:
WB

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Product Overview

Description

Prions cause neurodegenerative disease by aggregating extracellularly within the central nervous system which disrupt the normal tissue structure. This disruption is characterized by "holes" in the tissue with resultant spongy architecture. Two conformational isoforms exist, the normal cellular isoform (PrPC) and the infectious, scrapie isoform (PrPSC). Other histological changes include astrogliosis and the absence of an inflammatory reaction. Neurodegenerative symptoms can include convulsions, dementia, ataxia (balance and coordination dysfunction), and behavioral or personality changes.

Immunogen

Recombinant mouse PrP protein, aa 23-237.

Species Reactivity

Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP4385

Applications

WB

Application Notes

WB (1.0-10 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

1 mg/mL

Purification

Affinity chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Handling Advice

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

CD229

Official Name

LY9

Full Name

T-lymphocyte surface antigen Ly-9

Alternative Names

LY9; CD229; SLAMF3; hly9; mlymphocyte antigen 9

Gene ID

Uniprot ID

Publications

Publications (0)

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