NeuroMab™ Anti-GAD67, Clone L127/8 (CBP8229)

Product Overview

Immunogen

Fusion protein amino acids 1-594 (full-length) of human GAD67 (also known as Glutamate decarboxylase 1, 67 kDa glutamic acid decarboxylase, Glutamate decarboxylase 67 kDa isoform, GAD1, GAD and DCE1, accession number Q99259)
Mouse: 97% identity (577/594 amino acids identical)
Rat: 97% identity (577/594 amino acids identical)
100% identity (213/213 amino acids identical) with GAD25
>90% identity (366/391 amino acids identical, highest in N-terminus) with GAD44
>60% identity (375/569 amino acids identical, highest in C-terminus) with GAD2/GAD65/DCE2

Species Reactivity

Human; Rat; Mouse

Clonality

Monoclonal

Isotype

IgG2b

Clone Number

CBP8229

Applications

WB; IHC; ICC

Application Notes

Cross-reacts with GAD25;Does not cross-react with GAD44 or GAD65/GAD2

Conjugation

Unconjugated

Product Properties

Research Use Only

For reseaech use only, not for human or dignostic use.

Target

GAD1

Official Name

GAD1

Full Name

GAD67

Alternative Names

Glutamate Decarboxylase 1; Glutamate Decarboxylase 1 (Brain; 67kDa); Glutamate Decarboxylase 67 KDa Isoform; 7 KDa Glutamic Acid Decarboxylase; EC 4.1.1.15; GAD-67; GAD;

Uniprot ID

Q99259

Product Pictures

Fig. 1 Array tomography immunofluorescence of an Lowicrylembedded 70 nm section from adult mouse neocortex with L127/8 (green), guinea pig polyclonal GABA (Millipore AB175, magenta) and DAPI (blue).

Publications