NeuroMab™ Anti-GluN2C/NR2C, Clone N422/18 (CBP8253)

Product Overview

Immunogen

Fusion protein amino acids 836-1233 (cytoplasmic C-terminus) of rat GluN2C (also known as Glutamate receptor ionotropic NMDA 2C, Glutamate [NMDA] receptor subunit epsilon-3, Nmethyl D-aspartate receptor subtype 2C, NMDAR2C, NR2C and Grin2c, accession number Q00961)
Mouse: 93% identity (372/400 amino acids identical)
Human: 72% identity (293/405 amino acids identical)
<30% identity with GluN2D/NR2D and other GluN/NMDA receptors

Species Reactivity

Rat; Mouse; Human

Clonality

Monoclonal

Isotype

IgG1

Clone Number

CBP8253

Applications

WB; IHC; ICC

Conjugation

Unconjugated

Product Properties

Research Use Only

For reseaech use only, not for human or dignostic use.

Target

GluN2C

Official Name

GRIN2C

Full Name

GluN2C/NR2C glutamate receptor

Alternative Names

GRIN2C; GluN2C; NMDAR2C; NR2C; glutamate ionotropic receptor NMDA type subunit 2C

Uniprot ID

Q00961

Product Pictures

Fig. 1 Immunoblot versus crude membrane fractions from GluN2C/NR2C knockout (KO) and wild-type (WT) mouse cerebella probed with N422/18 (top) and tubulin (bottom).

Fig. 2 Immunofluorescence staining of sections from adult GluN2C/NR2C wild-type (WT) and knockout (KO) mouse cerebellum with N422/18 (GluN2C/NR2C, red) and L106/83 (Gephyrin, green) TC supe.