NeuroMab™ Anti-Kv4.2 potassium channel subunit, Clone L28/4 (CBP8325)

Product Overview

Immunogen

Fusion protein amino acids 471-630 (cytoplasmic C-terminus) of rat Kv4.2 (Potassium voltage-gated channel subfamily D member 2, Voltage-gated potassium channel subunit Kv4.2, Kcnd2, Kiaa1044, MNCb-7013, RK5 and Shal1, accession number Q63881)
Mouse: 99% identity (159/160 amino acids identical)
Human: 98% identity (157/160 amino acids identical)
<50% identity with Kv4.3

Species Reactivity

Human; Rat; Mouse

Clonality

Monoclonal

Isotype

IgG1

Clone Number

CBP8325

Applications

WB; IHC; ICC

Application Notes

Does not cross-react with Kv4.3 (based on KO validation results)

Research Areas

K+ channels

Conjugation

Unconjugated

Product Properties

Research Use Only

For reseaech use only, not for human or dignostic use.

Target

KCND2

Official Name

KCND2

Full Name

Kv4.2 K+ channel

Alternative Names

KCND2; KV4.2; RK5; potassium voltage-gated channel subfamily D member 2

Uniprot ID

Q63881

Product Pictures

Fig. 1 Immunoblot against crude brain membranes from adult rat (RBM) and wild-type (WT) and Kv4.2 knockout (KO) mice probed with L28/4 (left) or N52A/42 (right) TC supe.

Fig. 2 Immunoblot against crude membrane fractions from whole mouse (MBM) or rat (RBM) brain and from human hippocampus [HBM(H)], cerebellum [HBM(Cb)] or cerebral cortex [HBM(Cx)] and probed with L28/4 (left) or N52A/42 (right) TC supe.