NeuroMab™ Anti-Shank2/ProSAP1/Spank-3/CortBP1 scaffold protein,Clone N23B/6 (CBP8487)

Product Overview

Immunogen

Fusion protein amino acids 84-309 (SH3/PDZ domains) of rat Shank2 (SH3 and multiple ankyrin repeat domains protein 2; accession number Q9QX74)
Human: 94% identity (213/226 amino acids identical)
Mouse: 97% identity (220/226 amino acids identical)

Species Reactivity

Human; Mouse

Clonality

Monoclonal

Isotype

IgG1

Clone Number

CBP8487

Applications

WB; IHC; IP; ICC

Application Notes

No cross-reactivity against Shank1 or Shank3

Research Areas

Scaffolds

Conjugation

Unconjugated

Product Properties

Research Use Only

For reseaech use only, not for human or dignostic use.

Target

SHANK2

Official Name

SHANK2

Full Name

Shank2

Alternative Names

SH3 And Multiple Ankyrin Repeat Domains 2; Cortactin-Binding Protein 1; ProSAP1; CORTBP1; SH3 And Multiple Ankyrin Repeat Domains Protein 2; Proline-Rich Synapse Associated Protein 1; Proline-Rich Synapse-Associated Protein 1; Cortactin SH3 Domain-Binding Protein; GKAP/SAPAP Interacting Protein;

Uniprot ID

Q9QX74

Product Pictures

Fig. 1 Transfected cell immunoblot: extracts of COS-1 cells transiently transfected with Shank1, Shank2 or Shank3 plasmids and probed with N23B/6 TC supe (left panel) or a monoclonal lane loading control (right panel).

IHC

Fig. 2 Adult rat hippocampus immunohistochemistry.

Fig. 3 Immunoblots on brain membranes prepared from whole rat (RBM) and mouse (MBM) brain, and from human cerebral cortex [HBM(Cx)] and hippocampus [HBM(H)].

Publications