NoGeneST™ Anti-Cyclophilin B Aptamer, aCyclophilin-B aptamer-2 sodium

Name: NoGeneST™ Anti-Cyclophilin B Aptamer, aCyclophilin-B aptamer-2 sodium
SKU: NRYF-0625-HZ37
Rating: 5 (1 reviews)

[CAT#: NRYF-0625-HZ37]

A nucleic acid aptamer designed to specifically bind and inhibit the protein Cyclophilin B (CypB).

Target:: CypB

Type:: RNA

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Product Overview

Description

This is a synthetic nucleic acid aptamer engineered to target Cyclophilin B (CypB), an enzyme involved in protein folding and cellular signaling. By binding to CypB, this aptamer can inhibit its enzymatic isomerase activity or block its interactions with other signaling partners. This makes it a valuable molecular probe for investigating the diverse roles of CypB in pathological processes, including viral infections, inflammation, and cancer.

Type

RNA

Properties

Size

1 mg; 5 mg; 10 mg

Appearance

Supplied as a lyophilized white to off-white solid.

Purity

>90%

Shipping

Room temperature

Storage

Powder Form: Stable for 3 years when stored at -20°C.
In Solvent: Stable for 6 months when aliquoted and stored at -80°C

Research Use Only

For Research Use Only

Target Details

Target

CypB

Full Name

Cyclophilin B

Alternative Names

PPIB; CYP-S1; SCYLP

Gene ID

5479

Uniprot ID

P23284

Target Overview

Cyclophilin B (CypB) is a member of the cyclophilin family of enzymes known as peptidyl-prolyl cis-trans isomerases (PPIases). Primarily located in the endoplasmic reticulum, it plays a key role in ensuring the proper folding and trafficking of proteins within the cell. Beyond its intracellular functions, CypB can also be secreted, where it acts as a signaling molecule involved in inflammation, immune cell chemotaxis, and the replication cycle of certain viruses like Hepatitis C Virus (HCV). Its multifaceted role in both normal physiology and disease makes it a significant area of research and a potential therapeutic target.

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