NoGeneST™ Anti-GABRA1 Aptamer, aGABRA1 aptamer

Name: NoGeneST™ Anti-GABRA1 Aptamer, aGABRA1 aptamer
SKU: NRYF-0625-HZ97
Rating: 5 (1 reviews)

[CAT#: NRYF-0625-HZ97]

Aptamer designed to specifically recognize the alpha-1 subunit of the GABA-A receptor, a key target in neuroscience and epilepsy research.

Target:: GABRA1

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Product Overview

Relevant Diseases

Epilepsy

Properties

Size

5 nmol. 10 nmol. 50 nmol

Soluble In

PBS; buffer system with Serum; other

Purity

>90%

Shipping

Room temperature

Storage

Powder Form: Stable for 3 years when stored at -20°C.
In Solvent: Stable for 6 months when aliquoted and stored at -80°C

Research Use Only

For Research Use Only

Target Details

Target

GABRA1

Full Name

Gamma-Aminobutyric Acid Receptor Subunit Alpha-1

Gene ID

2554

Uniprot ID

P14867

Target Overview

GABRA1 codes for the alpha-1 subunit of the GABA-A (γ-aminobutyric acid type A) receptor. GABA-A receptors are ligand-gated ion channels that serve as the primary mediators of fast inhibitory neurotransmission in the central nervous system. The alpha-1 subunit is the most abundant alpha subunit isoform in the adult brain and is a critical component of receptor assembly and function. These receptors are the target for major classes of drugs, including benzodiazepines and barbiturates. Mutations in the GABRA1 gene that impair receptor function are a known cause of genetic epilepsy syndromes, highlighting the subunit's essential role in regulating neuronal excitability.

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