NoGeneST™ IRS-1-ASO, Antisense Oligonucleotide
[CAT#: NRYF-0625-XY64]
- Target:
- IRS1
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Overview
Description
IRS-1-ASO is a 25 mer DNA antisense oligonucleotide, which silences expression of insulin receptor substrate-1 (IRS-1).
Species
Human
Applications
Studies insulin resistance in Alzheimer's disease (AD) and type 2 diabetes-related cognitive decline. By targeting IRS-1, explores its role in neuronal insulin signaling, amyloid-beta clearance, and tau phosphorylation. Ideal for in vitro (neuronal cultures) and in vivo (diabetes/AD mouse models).
Relevant Diseases
Type 2 diabetes mellitus
Properties
Appearance
Solid
Shipping
Room temperature
Storage
Store at -20°C, sealed and away from moisture.
In solvent, store at -80°C for up to 6 months, or -20°C for up to 1 month (sealed and away from moisture).
In solvent, store at -80°C for up to 6 months, or -20°C for up to 1 month (sealed and away from moisture).
Research Use Only
For research use only.
Target Details
Target
IRS1
Official Name
IRS1
Full Name
Insulin Receptor Substrate 1
Alternative Names
HIRS-1; IRS-1
Publications
Publications (0)
Neural Antibodies
Neural Genes
For Research Use Only. Not For Clinical Use.
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