iNeu™ Human Motor Neurons (TDP-43 mutation, M337V, HOM)

[CAT#: NCL-2105-P136-IX]

These cells can be used for disease modeling, drug screening and toxicology testing.

Species:: Human

Cell Types:: Motor Neurons

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Product Overview

Description

Human iPSC-derived Motor Neurons (TDP-43 mutation, M337V, HOM) from Creative Biolabs are isolated from Human iPSC-derived motor neurons (TDP-43 mutation, Q331K, heterozygous). They are cryopreserved after purification and delivered frozen.

Neurological Disease Models

ALS-related Cells

Cell Types

Motor Neurons

Application Notes

Media
Human Motor Neuron Maintenance Medium (Cat # NCL-2105-P131-IX)

Relevant Diseases

Amyotrophic Lateral Sclerosis

Species

Human

Properties

Size

Each vial contains>1 x 10e6 cells.

Freeze Medium

90% FBS+10% DMSO

Tissue Source

Human iPSC-derived motor neurons (TDP-43 mutation, Q331K, heterozygous)

Cell Purity

>95%

Cell Viability

>90%

Mycoplasma Testing

Negative

Sterility Testing

The cell line has been screened using the membrane filtration testing methods to confirm the absence of aerobic, anaerobic and fungi microorganisms.

Genetic Stability Testing

We perform cell genetic stability studies under ICH guidelines. We can provide guidance on the appropriate testing program upon your requirements.

Shipping

Frozen on dry ice

Storage

Liquid nitrogen immediately upon delivery

Handling Advice

Frozen cells should be thawed immediately upon receipt and grown according to handling procedure to ensure cell viability and proper assay performance.
Note: Do not freeze the cells upon receipt as it may result in irreversible damage to the cell line.