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Creative Biolabs

Mouse Anti-GSK3 Alpha (CBP1954)

[CAT#: NAB2007FY449]

Mouse Monoclonal [W0043] to GSK3 Alpha (pSer21)

Host Species:
Mouse
Species Reactivity:
Human
Applications:
WB

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Product Overview

Description

When phosphorylated at serine 21, the mouse anti-GSK3α antibody recognizes glycogen synthase kinase 3α (also known as serine/threonine protein kinase GSK3A). 1993) and CREB (Fiol et al., 1994) and glycogen metabolism (Welsh and Proud, 1993). It has also been reported that this kinase regulates the proteolysis and localization of cyclin D1 (Diehl et al., 1998). Phosphorylation of GSK3 at Serine 21 leads to inactivation of this kinase (Frame et al., 2001), and is associated with poor survival of patients with acute myeloid leukemia (AML).

Immunogen

Phosphopeptide coupled with KLH

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP1954

Applications

WB

Application Notes

WB (1/1000)

Relevant Diseases

Parkinson's Disease

Research Areas

Neuroregeneration

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS; 0.09% Sodium Azide
PEG & Sucrose

Preservatives

Yes

Purification

Thiophillic adsorption and size exclusion chromatography from tissue culture supernatant.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

GSK3A

Official Name

GSK3A

Full Name

Glycogen Synthase Kinase 3 Alpha

Alternative Names

Glycogen Synthase Kinase 3 Alpha; EC 2.7.11.26; Serine/Threonine-Protein Kinase GSK3A; GSK-3 Alpha; EC 2.7.11.1; EC 2.7.11

Gene ID

2931(Human); 606496(Mouse); 50686(Rat)

Uniprot ID

P49840(Human); Q2NL51(Mouse); P18265(Rat)
Publications

Publications (0)

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