Product
Anti-Tubulin Monoclonal Antibody (CBP2384)
[CAT#: NAB2010404LS]
Anti-Tubulin Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Mouse; Human
- Applications:
- WB
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Eukaryotic microtubules are tubular polymers of tubulin that are a major component of the cytoskeleton. They play an essential role in diverse cellular functions, including migration, mitosis, and trafficking, and are also critical for normal development. β- and α-tubulins comprise the two core protein families that heterodimerize and assemble into each microtubule filament. There are multiple β- and α-tubulins isotypes, with each showing unique tumoral and tissue-specific distribution. TUBB4A is a β-tubulin primarily expressed in nervous tissue and moderate expression in testis. Mutations in TUBB4A cause hypermyelinating leukodystrophy-6 and autosomal dominant torsion dystonia -4.
Immunogen
Full length protein expressed in HEK293T cells transfected with human TUBB4 expression vector.
Species Reactivity
Mouse; Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG2b
Clone Number
CBP2384
Applications
WB
Application Notes
WB (0.1-1.0 µg/mL)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide.
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Handling Advice
Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Target
Tubulin
Official Name
Tubulin
Full Name
Tubulin
References
1. Arai-Ichinoi N, et al. 2016. Hum. Genet. 135: 89.
2. Romaniello R, et al. 2015. Brain Dev. 37: 273.
3. Shimojima K, et al. 2015. Brain Dev. 37: 281.
2. Romaniello R, et al. 2015. Brain Dev. 37: 273.
3. Shimojima K, et al. 2015. Brain Dev. 37: 281.
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
