Product Overview

Immunogen

Purified recombinant fragment (aa 120-292) of human CDK5 expressed in E.coli.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP2401

Applications

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Handling Advice

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

CDK5

Official Name

CDK5

Full Name

Cyclin Dependent Kinase 5

Alternative Names

Cyclin Dependent Kinase 5; Serine/Threonine-Protein Kinase PSSALRE; Tau Protein Kinase II Catalytic Subunit; Cell Division Protein Kinase 5; TPKII Catalytic Subunit; Cyclin-Dependent-Like Kinase 5; Protein Kinase CDK5 Splicing;

Gene ID

1020 (Human); 12568 (Mouse); 140908 (Rat)

Uniprot ID

Q00535 (Human); P49615 (Mouse); Q03114 (Rat)

References

1. Wilkaniec A, et al. 2015. J. Neurochem. 10.1111/jnc.13365.
2. Liu SL, et al. 2015. Mol. Neurobiol.
3. Lai KO, et al. 2015. Mini. Rev. Med. Chem. 15:390.
4. Ye T, et al. 2012. Int. Rev. Neurobiol. 105:91.
5. Cheung ZH, et al. 2012. Trends Cell Biol. 22:169.
6. Lalioti V, et al. 2010. Cell Cycle 9:284.
7. Slevin M, et al. 2009. Curr. Opin. Pharmacol. 9:119.
8. Dhavan R, et al. 2001. Nat. Rev. Mol. Cell. Biol. 2:749.
9. Pareek TK, et al. 2010. J. Exp. Med. 207:2507.

Publications