Mouse Anti-Gemin 2 Monoclonal Antibody (CBP2491)

Product Overview

Description

Gemin 2 is a component of the survival of motor neurons (SMN) macromolecule protein complex, which plays an important role in the assembly and re-structuring of small nucleoproteins and transcriptosomes. The SMN complex localizes to the cytosol and nucleus of eukaryotic cells. Gemin 2 is the only gemin protein that has no homology to any other gemins. Recent studies have suggested that the role of Gemin 2 is to organize 5 Sm proteins into a partial ring for snRNA binding.

Species Reactivity

Human; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP2491

Applications

WB; ICC

Application Notes

WB (2.0-10 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

The antibody solution should be stored undiluted between 2°C and 8°C.

Handling Advice

Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected from prolonged exposure to light.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

Gemin 2

Official Name

GEMIN2

Full Name

Gem Nuclear Organelle Associated Protein 2

Alternative Names

Gem Nuclear Organelle Associated Protein 2; Survival Of Motor Neuron Protein Interacting Protein 1; Component Of Gems 2; Gemin-2; SIP1; Survival Of Motor Neuron Protein-Interacting Protein 1;