Product
Mouse Anti-Gemin 2 Monoclonal Antibody (CBP2491)
[CAT#: NAB2010614LS]
Anti Gemin 2 Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human; Rat
- Applications:
- WB; ICC
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Gemin 2 is a component of the survival of motor neurons (SMN) macromolecule protein complex, which plays an important role in the assembly and re-structuring of small nucleoproteins and transcriptosomes. The SMN complex localizes to the cytosol and nucleus of eukaryotic cells. Gemin 2 is the only gemin protein that has no homology to any other gemins. Recent studies have suggested that the role of Gemin 2 is to organize 5 Sm proteins into a partial ring for snRNA binding.
Species Reactivity
Human; Rat
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1, κ
Clone Number
CBP2491
Applications
WB; ICC
Application Notes
WB (2.0-10 µg/mL)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide.
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
The antibody solution should be stored undiluted between 2°C and 8°C.
Handling Advice
Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected from prolonged exposure to light.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Target
Gemin 2
Official Name
GEMIN2
Full Name
Gem Nuclear Organelle Associated Protein 2
Alternative Names
Gem Nuclear Organelle Associated Protein 2; Survival Of Motor Neuron Protein Interacting Protein 1; Component Of Gems 2; Gemin-2; SIP1; Survival Of Motor Neuron Protein-Interacting Protein 1;
References
1. Battle D, et al. 2007. J Biol Chem. 282(38):27953
2. Gupta K, et al. 2015. J Biol Chem. 290(33):20185
2. Gupta K, et al. 2015. J Biol Chem. 290(33):20185
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
