Mouse Anti-SMN2 Monoclonal Antibody (CBP2621)
[CAT#: NAB20101695CR]
Mouse Monoclonal (2C6D9) to SMN2
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- FC; IF; IHC; IP; WB; ELISA
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
The survival of motor neurons (SMN) genes are the disease genes of spinal muscular atrophy (SMA), a common motor neuron degenerative disease. The level of SMN protein correlates with phenotypic severity of SMA. SMA patients lack a functional SMN1 gene, but they possess an intact SMN2 gene, which though nearly identical to SMN1, is only partially functional, because a large majority of SMN2 transcripts lack exon 7, resulting in production of a truncated, less stable SMN protein.
Expression Host
Mammalian cells
Immunogen
SMN (Human-Specific) fusion protein Ag14333
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG2a
Clone Number
CBP2621
Applications
FC; IF; IHC; IP; WB; ELISA
Application Notes
IF : 1:20-1:200; IHC : 1:20-1:200; IP : 0.5-4.0 ug; WB : 1:500-1:1000
Research Areas
Neural Signal Transduction
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS, 0.1% sodium azide and 50% glycerol pH 7.3.
Preservatives
Yes
Concentration
1000 μg/ml
Purification
Antigen affinity purification
Purity
>95%, as determined by SDS-PAGE
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store at -20°C. Stable for one year after shipment.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Publications
Publications (0)
Neural Cell Lines
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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