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Creative Biolabs

Mouse Anti-SMN2 Monoclonal Antibody (CBP2622)

[CAT#: NAB20101696CR]

Mouse Monoclonal (3C10B5) to SMN2

Host Species:
Mouse
Species Reactivity:
Human; Mouse; Rat
Applications:
IF; WB; ELISA

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Product Overview

Description

The survival of motor neurons (SMN) genes are the disease genes of spinal muscular atrophy (SMA), a common motor neuron degenerative disease. The level of SMN protein correlates with phenotypic severity of SMA. SMA patients lack a functional SMN1 gene, but they possess an intact SMN2 gene, which though nearly identical to SMN1, is only partially functional, because a large majority of SMN2 transcripts lack exon 7, resulting in production of a truncated, less stable SMN protein.

Expression Host

Mammalian cells

Immunogen

SMN (Human,Mouse,Rat) fusion protein Ag14333

Species Reactivity

Human; Mouse; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2b

Clone Number

CBP2622

Applications

IF; WB; ELISA

Application Notes

IF : 1:20-1:200; WB : 1:500-1:1000

Research Areas

Growth and Development

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

1000 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

SMN2

Official Name

SMN2

Full Name

Survival of motor neuron 2, centromeric

Alternative Names

Component of gems 1; Gemin 1; SMN; SMN1; SMN1; SMN; SMN2; SMNC; SMNT; Survival motor neuron protein

Gene ID

6607(Human); 20595(Mouse)

Uniprot ID

Q16637(Human); P97801(Mouse)
Publications

Publications (0)

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