Mouse Anti-CD34 Monoclonal Antibody (CBP2630)

Product Overview

Description

CD34 is a commonly used marker for identifying human hematopoietic stem/progenitor cells and mediates cell adhesion and lymphocyte homing by binding L-selectin and E-selectin ligands. CD34 is also one of the best negative selection markers for characterizing and/or isolating human MSCs from bone marrow and other sources. Along with other positive selection markers (such as CD29, CD44, CD90, CD105 and CD166), negative selection markers (such as CD34 and CD45) are used for MSC identification.

Expression Host

Mammalian cells

Immunogen

CD34 fusion protein Ag5996

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP2630

Applications

IHC; ELISA

Application Notes

IHC : 1:20-1:200

Research Areas

Growth and Development

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

1000 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

CD34

Official Name

CD34

Full Name

CD34 molecule

Alternative Names

CD34; CD34 molecule

Gene ID

947(Human); 12490(Mouse); 305081(Rat)

Uniprot ID

P28906(Human); Q64314(Mouse)

References

1. Jiang, X., Du, Y., Meng, X., Zhang, H., Zhao, D., Zhao, L.,... & Jiang, H. (2018). Low-Dose Radiation Enhanced Inhibition of Breast Tumor Xenograft and Reduced Myocardial Injury Induced by Doxorubicin. Dose-Response, 16(4), 1559325818813061. 2. Xie, C., Zhu, J., Wang, X., Chen, J., Geng, S., Wu, J.,... & Li, X. (2019). Tobacco smoke induced hepatic cancer stem cell-like properties through IL-33/p38 pathway. Journal of Experimental & Clinical Cancer Research, 38(1), 1-13. 3. Lv, S., Wang, N., Lv, H., Yang, J., Liu, J., Li, W. P.,... & Chen, Z. J. (2019). The attenuation of trophoblast invasion caused by the downregulation of EZH2 is involved in the pathogenesis of human recurrent miscarriage. Molecular Therapy-Nucleic Acids, 14, 377-387.

Publications