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Creative Biolabs

Mouse Anti-VCP Monoclonal Antibody (CBP2663)

[CAT#: NAB20101737CR]

Mouse Monoclonal (2A4B10) to VCP

Host Species:
Mouse
Species Reactivity:
Human; Mouse
Applications:
IF; IHC; WB; ELISA

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Product Overview

Description

VCP(Valosin-containing protein) belongs to the AAA ATPase family. VCP was first identified as a result of attempts to clone a putative peptide hormone called valosin. It was found that the cloned cDNA encoded a ubiquitously expressed 90 kDa cytosolic protein, termed VCP, which showed none of the characteristics of a peptide hormone precursor(PMID:1382975). Defects in VCP are the cause of inclusion body myopathy with early-onset Paget disease and frontotemporal dementia (IBMPFD) and amyotrophic lateral sclerosis type 14 with or without frontotemporal dementia (ALS14). VCP has a calculated molecular weight of 89 kDa and an apparent molecular weight of 90-100 kDa.

Expression Host

Mammalian cells

Immunogen

VCP fusion protein Ag1002

Species Reactivity

Human; Mouse

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP2663

Applications

IF; IHC; WB; ELISA

Application Notes

IF : 1:20-1:200; IHC : 1:20-1:200; WB : 1:500-1:1000

Research Areas

Neural Cell

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

667 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

VCP

Official Name

VCP

Full Name

Valosin-containing protein

Alternative Names

15S Mg(2+) ATPase p97 subunit; IBMPFD; p97; TER ATPase; TERA; valosin containing protein; VCP

Gene ID

7415(Human); 269523(Mouse); 116643(Rat)

Uniprot ID

P55072(Human); Q01853(Mouse); P46462(Rat)
Publications

Publications (0)

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