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Mouse Anti-VIM Monoclonal Antibody (CBP2669)

[CAT#: NAB20101743CR]

Mouse Monoclonal (3H9D1) to VIM

Host Species:
Mouse
Species Reactivity:
Human; Mouse; Rat
Applications:
FC; IF; IHC; WB; ELISA

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Product Overview

Description

Vimentin belongs to the intermediate filament family. Vimentin is class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is important for stabilizing the architecture of the cytoplasm. Monocyte-derived macrophages secrete vimentin into the extracellular space in vitro. Secretion of vimentin was enhanced by the proinflammatory cytokine tumor necrosis factor-alpha (TNFA; 191160) and inhibited by the antiinflammatory cytokine IL10 (124092), suggesting that vimentin is involved in the immune response. Vimentin has specialized functions that contribute to specific dynamic cellular processes. As a phosphoprotein, 55-60 kDa of vimentin proteins can be observed due to the different phosphorylation level.

Expression Host

Mammalian cells

Immunogen

Vimentin fusion protein Ag0489

Species Reactivity

Human; Mouse; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP2669

Applications

FC; IF; IHC; WB; ELISA

Application Notes

IF : 1:20-1:200; IHC : 1:20-1:200; WB : 1:500-1:1000

Research Areas

Metabolism

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

800 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

Vimentin

Official Name

VIM

Full Name

Vimentin

Alternative Names

CTRCT30;
Epididymis luminal protein 113;
FLJ36605;
HEL113;
VIM;

Gene ID

7431(Human); 22352(Mouse); 81818(Rat)

Uniprot ID

P08670(Human); P20152(Mouse); P31000(Rat)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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