Mouse Anti-C1qC Monoclonal Antibody (CBP2733)

[CAT#: NAB20101809CR]

Mouse Monoclonal (1C5B4) to C1qC

Host Species:: Mouse

Species Reactivity:: Human

Applications:: WB; ELISA

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Product Overview

Description

The first component of complement, C1, is a calcium-dependent complex of the 3 subcomponents C1q, C1r, and C1s. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. This antibody is raised against C1qC which is the C-chain polypeptide of human complement subcomponent C1q.

Expression Host

Mammalian cells

Immunogen

C1qC fusion protein Ag10233

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgM

Clone Number

CBP2733

Applications

WB; ELISA

Application Notes

WB : 1:500-1:1000

Research Areas

Metabolism

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

680 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

C1QC

Official Name

C1QC

Full Name

Complement component 1, q subcomponent, C chain

Alternative Names

C1Q C; C1qC; C1QG

Gene ID

714(Human)

Uniprot ID

P02747(Human)

References

1. Alberts, A., Klingberg, A., Wessig, A. K., Combes, C., Witte, T., Brand, K.,... & Neumann, K. (2020). C-reactive protein (CRP) recognizes uric acid crystals and recruits proteases C1 and MASP1. Scientific reports, 10(1), 1-13.

Publications