Mouse Anti-ITGB1 Monoclonal Antibody (CBP2743)

Product Overview

Description

Integrin beta-1 (ITGB1) is a 130 kDa single chain type I glycoprotein that is expressed in a heterodimeric complex with one of six distinct α subunits, comprising the very late activation antigen (VLA) subfamily of adhesion receptors. It is one of the essential surface molecules expressed on human MSC from bone marrow and other sources. The β1 subunit is also broadly expressed on lymphocytes and monocytes, weakly expressed on granulocytes, and not expressed on erythrocytes. These receptors are involved in a variety of cell-cell and cell-matrix interactions.

Expression Host

Mammalian cells

Immunogen

Integrin Beta 1 fusion protein Ag24476

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP2743

Applications

FC; WB; ELISA

Application Notes

WB : 1:500-1:1000

Research Areas

Neuroendocrinology

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

1000 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

CD29

Official Name

ITGB1

Full Name

Integrin Beta 1

Alternative Names

CD29;
FNRB;
Integrin beta 1;
ITGB 1;
ITGB1;
MDF2;
MSK12;
VLAB;

Gene ID

3688(Human); 16412(Mouse)

Uniprot ID

P05556(Human); P09055(Mouse)

References

1. Wang, X., Adegoke, E. O., Ma, M., Huang, F., Zhang, H., Adeniran, S. O.,... & Zhang, G. (2019). Influence of Wilms' tumor suppressor gene WT1 on bovine Sertoli cells polarity and tight junctions via non-canonical WNT signaling pathway. Theriogenology, 138, 84-93. 2. Zhong, B., Wang, K., Xu, H., & Kong, F. (2018). Silencing Formin-like 2 inhibits growth and metastasis of gastric cancer cells through suppressing internalization of integrins. Cancer cell international, 18(1), 1-10.

Publications