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Creative Biolabs
Product

Mouse Anti-CRX Monoclonal Antibody (CBP2971)

[CAT#: NAB20102049CR]

Mouse Monoclonal (1C3C11) to CRX

Host Species:
Mouse
Species Reactivity:
Human; Mouse; Rat; Porcine
Applications:
WB; ELISA

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Product Overview

Description

Cone-rod homeobox (Crx) is a homeodomain transcription factor and member of the Otx family, which has been thought to play a critical role in determining and maintaining the phenotype of both pinealocytes and retinal photoreceptors [PMID:17467693]. In the mammalian retina, Crx plays an essential role in the normal development and maintenance of cones and rods and regulates expression of the network of genes that characterize the retina [PMID:17653270]. Elimination of Crx by disruption of the homeobox domain results in loss of the image-forming visual system but not the non-image-forming visual system controlling circadian rhythms.

Expression Host

Mammalian cells

Immunogen

CRX fusion protein Ag30086

Species Reactivity

Human; Mouse; Rat; Porcine

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP2971

Applications

WB; ELISA

Application Notes

WB : 1:500-1:1000

Research Areas

Neuron

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

1000 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

CRX

Official Name

CRX

Full Name

Cone-rod homeobox

Alternative Names

Cone rod homeobox; Cone rod homeobox protein; CORD2; CRD; CRX; LCA7; OTX3

Gene ID

1406(Human)

Uniprot ID

O43186(Human)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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