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Creative Biolabs

Anti-NTRK2 Monoclonal Antibody (CBP3700)

[CAT#: NAB201239LS]

Anti-NTRK2 Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Human; Rat
Applications:
WB

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Product Overview

Description

NTRK2 (Neurotrophic Tyrosine Kinase, Receptor, type 2), also known as TrkB, is one of the members of the neurotrophin receptor family, which include TrkA and TrkC. All three Trk proteins exhibit a conserved subdomain that contains a signal peptide, two cysteine rich domains, a cluster of three leucine rich motifs, and two Ig-like domains in the extracellular portion. It has been shown that Trk receptor-mediated neurotrophic signaling regulates neuron physiology, cell proliferation and survival, axon and dendrite growth and patterning, and synaptic plasticity.

Immunogen

Purified recombinant full length of human NTRK2

Species Reactivity

Human; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2a, κ

Clone Number

CBP3700

Applications

WB

Application Notes

WB (0.1-1 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

0.5 mg/mL

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

NTRK2

Official Name

NTRK2

Full Name

Tropomyosin receptor kinase B

Alternative Names

NTRK2; GP145-TrkB; TRKB; trk-B; neurotrophic receptor tyrosine kinase 2; OBHD; EIEE58

Gene ID

18212(Mouse); 25054(Rat)

Uniprot ID

P15209(Mouse); Q63604(Rat)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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