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Creative Biolabs

Mouse Anti-Mouse CD209a Monoclonal Antibody (CBP3853)

[CAT#: NAB2012376LS]

Anti-CD209a Monoclonal Antibody [PE]

Host Species:
Mouse
Species Reactivity:
Mouse
Applications:
FC

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Product Overview

Description

CD209a, is also known as Dendritic Cell-Specific Intercellular adhesion molecule 3 (ICAM-3)-Grabbing Nonintegrin (DC-SIGN) and CIRE. CD209a is the mouse homolog of human CD209, and is expressed on myeloid dendritic cells, placental macrophages, liver and placental endothelial cells. CD209 binds to ICAM-3 (CD50), ICAM-2 (CD102), and Butyrophilin (BTN2A1), and mediates dendritic cell migration and T cell proliferation. It plays a critical role in capturing and internalizing pathogens such as Streptococcus pneumoniae.

Immunogen

This monoclonal antibody was raised against a purified extracellular domain of mouse CD209a (DC-SIGN)-IgG1 Fc fusion protein.

Species Reactivity

Mouse

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2c

Clone Number

CBP3853

Applications

FC

Application Notes

FCM (≤ 1.0 μg per million cells in 100 µL volume)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Alexa Fluor 594; Alexa Fluor 488; Alexa Fluor 498; Alexa Fluor 647; Alexa Fluor 700; APC; APC/Cyanine 7; APC/Fire 750; Biotin; Brilliant Violet 421; Brilliant Violet 510; Brilliant Violet 570; Brilliant Violet 570; Brilliant Violet 605; Brilliant Violet 650; Brilliant Violet 711; Brilliant Violet 750; Brilliant Violet 785; FITC; HRP; PE; Pacific Blue; PE/Cyanine 5; PE/Cyanine 7; PerCP; Spark YG 570
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA.

Concentration

1.0 mg/mL

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

CD209a

Official Name

CD209

Full Name

CD209 molecule

Alternative Names

CD209 antigen like protein B;
CD209b antigen;
DC SIGN related protein 1;
DC SIGNR1;
OtB7;

Gene ID

69165(Mouse)

Uniprot ID

Q8CJ91(Mouse)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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