Mouse Anti-Human DC-SIGN/L-SIGN Monoclonal Antibody (CBP3997)
[CAT#: NAB20121003LS]
Anti-DC-SIGN/L-SIGN Monoclonal Antibody [Unconjugated ]
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- FC
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
DC-SIGN is a C-type lectin with high affinity for ICAM3 molecules. It binds various microorganisms by recognizing the high mannose glycoprotein on the envelope. It is particularly useful as a receptor for many viruses (such as HIV and hepatitis C). L-SIGN is a transmembrane receptor, which is called L-SIGN due to its expression in the endothelial cells of lymph nodes and liver. This protein is related to the innate immune system and can recognize a variety of evolutionary pathogens ranging from parasites to viruses. The protein is organized into three different domains: the N-terminal transmembrane domain, the tandem repeat neck domain and the C-type lectin carbohydrate recognition domain.
Immunogen
DC-SIGN DNA.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG2b, κ
Clone Number
CBP3997
Applications
FC
Application Notes
FCM (≤0.5 µg per million cells in 100 µL volume)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation; Neurodegeneration
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide.
Concentration
1.0 mg/mL
Purification
Affinity Chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Publications
Publications (0)
For Research Use Only. Not For Clinical Use.
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