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Creative Biolabs

Mouse Anti-Human Granzyme A Monoclonal Antibody (CBP4014)

[CAT#: NAB20121027LS]

Anti-Granzyme A Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Human
Applications:
FC; ICC; IP; IHC-P

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Product Overview

Description

Granzyme A is a 28 kD disulfide-linked homodimeric protein and the most abundant of the proteases occurring in CTL granules. It is homologous to other serine esterases, including other granyzmes, mast cell proteases, and neutrophil cathepsins. Granzyme B is thought to be a rapidly-acting apoptotic enzyme, while Granzyme A is slow acting.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP4014

Applications

FC; ICC; IP; IHC-P

Application Notes

FCM (≤ 0.5 µg per million cells in 100 µL volume)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA.

Concentration

1.0 mg/mL

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

Granzyme A

Official Name

GZMA

Full Name

Granzyme A

Alternative Names

GZMA; CTLA3; HFSP; granzyme A

Gene ID

3001 (Human); 14938 (Mouse)

Uniprot ID

P12544 (Human); P11032 (Mouse)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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