Mouse Anti-HSPA1L Monoclonal Antibody (CBP4259)
[CAT#: NAB210129LS]
Anti-HSPA1L Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human; Rat
- Applications:
- WB
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
Product Overview
Description
HSPA1L is a chaperone protein belonging to the heat shock protein 70 (HSP70) family. HSPA1L participates in multiple biological processes, such as apoptosis, cell growth and differentiation, by facilitating the folding of newly-translated proteins and the degradation of misfolded proteins. Overexpression of HSPA1L mitigates symptoms of neurodegenerative diseases including Alzheimer's Diseases, and Parkinson's diseases, suggesting that HSPA1L has the potential to serve as a diagnostic/prognostic biomarker for these disorders.
Species Reactivity
Human; Rat
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG2b, κ
Clone Number
CBP4259
Applications
WB
Application Notes
WB (0.5-2.0 µg/mL)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation; Neurodegeneration
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
0.01 M PBS, pH 7.4, containing 0.02% NaN3, 50% glycerol.
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Handling Advice
Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
References
1. Huusko JM, et al. 2018. PLoS Genet. 14(7):e1007394
2. Lee JH, et al. 2017. Oncogene. 36(47):6555
3. Takahashi S, et al. 2017, Genome Med. 9(1):8
2. Lee JH, et al. 2017. Oncogene. 36(47):6555
3. Takahashi S, et al. 2017, Genome Med. 9(1):8
Biomaterials
Neural Antibodies
For Research Use Only. Not For Clinical Use.
