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Creative Biolabs
Product

Mouse Anti-HSPA1L Monoclonal Antibody (CBP4259)

[CAT#: NAB210129LS]

Anti-HSPA1L Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Human; Rat
Applications:
WB

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Product Overview

Description

HSPA1L is a chaperone protein belonging to the heat shock protein 70 (HSP70) family. HSPA1L participates in multiple biological processes, such as apoptosis, cell growth and differentiation, by facilitating the folding of newly-translated proteins and the degradation of misfolded proteins. Overexpression of HSPA1L mitigates symptoms of neurodegenerative diseases including Alzheimer's Diseases, and Parkinson's diseases, suggesting that HSPA1L has the potential to serve as a diagnostic/prognostic biomarker for these disorders.

Species Reactivity

Human; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2b, κ

Clone Number

CBP4259

Applications

WB

Application Notes

WB (0.5-2.0 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

0.01 M PBS, pH 7.4, containing 0.02% NaN3, 50% glycerol.

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Handling Advice

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

HSPA1L

Official Name

HSPA1L

Full Name

Heat shock 70 kDa protein 1L

Alternative Names

HSPA1L; HSP70-1L; HSP70-HOM; HSP70T; hum70t; heat shock protein family A (Hsp70) member 1 like

Gene ID

Uniprot ID

References

1. Huusko JM, et al. 2018. PLoS Genet. 14(7):e1007394
2. Lee JH, et al. 2017. Oncogene. 36(47):6555
3. Takahashi S, et al. 2017, Genome Med. 9(1):8
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For Research Use Only. Not For Clinical Use.
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