Mouse Anti-Human FGF-basic Monoclonal Antibody (CBP4285)

Product Overview

Description

Fibroblast growth factor-basic (also known as FGF-b, FGF-2) is a heparin-binding growth factor, which stimulates the proliferation of a wide variety of cells including mesenchymal, neuroectodermal, and endothelial cells. FGF-basic also exerts a potent angiogenic activity in vivo. FGF-basic has been isolated from neural, pituitary, adrenal cortex, and placental tissues. The BHFB15 antibody reacts with human fibroblast growth factor - basic (FGF-basic).

Immunogen

Recombinant human FGF-basic.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP4285

Applications

ELISA

Application Notes

ELISA (2.0 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Handling Advice

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

FGF2

Official Name

FGF2

Full Name

basic fibroblast growth factor

Alternative Names

FGF2; BFGF; FGF-2; FGFB; HBGF-2; fibroblast growth factor 2

Gene ID

1009

Uniprot ID

P09038(Human); P15655(Mouse)

References

1. Fitzgerald KA, et al. 2013. The Cytokine Factsbook. Acadmic Press. San Diego.
2. Klagsbrun M, 1992. Semin. Cancer Biol. 3:81.
3. Goldfarb M. 1990. Cell Growth Factor. 1:439.
4. Sensenbrenner M. 1993. Prog. Neurobiol. 6:683.

Publications