NoGeneST™ Anti-Aβ Aptamer, aAβ aptamer

Name: NoGeneST™ Anti-Aβ Aptamer, aAβ aptamer
SKU: NRYF-0625-HZ82
Rating: 5 (1 reviews)

[CAT#: NRYF-0625-HZ82]

Aptamer engineered to specifically bind amyloid-beta peptides, targeting a key pathological agent in Alzheimer's disease.

Target:: Aβ

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Product Overview

Species

Human

Relevant Diseases

Alzheimer's Disease

Properties

Size

5 nmol. 10 nmol. 50 nmol

Soluble In

PBS; buffer system with Serum; other

Purity

>90%

Shipping

Room temperature

Storage

Powder Form: Stable for 3 years when stored at -20°C.
In Solvent: Stable for 6 months when aliquoted and stored at -80°C

Research Use Only

For Research Use Only

Target Details

Target

Aβ

Full Name

Amyloid Beta Peptide

Gene ID

351

Uniprot ID

P05067

Target Overview

Amyloid beta (Aβ) is a peptide, typically 36-43 amino acids in length, which is derived from the proteolytic cleavage of the much larger Amyloid Precursor Protein (APP). While Aβ's physiological function is not fully resolved, its role in pathology is central to Alzheimer's disease. The Aβ monomer has a high propensity to misfold and aggregate, forming soluble oligomers, fibrils, and eventually the dense, insoluble amyloid plaques found in the brains of Alzheimer's patients. This aggregation process is considered a primary toxic event that initiates a cascade of neurodegeneration, making Aβ and its various aggregated forms a critical target for therapeutic and diagnostic development.

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