NoGeneST™ Anti-DISC1 Aptamer, aDISC1 aptamer

Name: NoGeneST™ Anti-DISC1 Aptamer, aDISC1 aptamer
SKU: NRYF-0625-HZ125
Rating: 5 (1 reviews)

[CAT#: NRYF-0625-HZ125]

Aptamer designed to specifically recognize DISC1, a scaffolding protein implicated as a major risk factor for schizophrenia and other psychiatric disorders.

Target:: DISC1

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Product Overview

Relevant Diseases

Schizophrenia

Properties

Size

5 nmol. 10 nmol. 50 nmol

Soluble In

PBS; buffer system with Serum; other

Purity

>90%

Shipping

Room temperature

Storage

Powder Form: Stable for 3 years when stored at -20°C.
In Solvent: Stable for 6 months when aliquoted and stored at -80°C

Research Use Only

For Research Use Only

Target Details

Target

DISC1

Full Name

Disrupted In Schizophrenia 1 Protein

Gene ID

27185

Uniprot ID

Q9RIA5

Target Overview

Disrupted in Schizophrenia 1 (DISC1) is a scaffolding protein that plays a critical role in the brain by coordinating a wide range of signaling pathways essential for neurodevelopment. Its functions include regulating neuronal proliferation, differentiation, migration, and synaptic integration. The DISC1 gene was famously identified through its disruption by a chromosomal translocation in a Scottish family with a high incidence of major mental illness. It has since become one of the most significant and widely studied genetic risk factors for a spectrum of severe psychiatric disorders, including schizophrenia, bipolar disorder, and major depression.

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