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Creative Biolabs

NoGeneST™ Anti-MOG Aptamer, aMOG aptamer

[CAT#: NRYF-0625-HZ106]

Aptamer designed to specifically recognize Myelin Oligodendrocyte Glycoprotein, a key autoantigen in demyelinating neurological diseases.

Target:
MOG

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Product Overview

Relevant Diseases

Multiple Sclerosis
Properties

Size

5 nmol. 10 nmol. 50 nmol

Soluble In

PBS; buffer system with Serum; other

Purity

>90%

Shipping

Room temperature

Storage

Powder Form: Stable for 3 years when stored at -20°C.
In Solvent: Stable for 6 months when aliquoted and stored at -80°C

Research Use Only

For Research Use Only
Target Details

Target

MOG

Full Name

Myelin Oligodendrocyte Glycoprotein

Gene ID

4340

Uniprot ID

Q16653

Target Overview

Myelin Oligodendrocyte Glycoprotein (MOG) is a protein located on the surface of oligodendrocytes and the outermost layer of myelin sheaths within the central nervous system. While its precise physiological function is still being fully determined, MOG is critically important in neuropathology as a primary target for the immune system in certain autoimmune demyelinating diseases. The presence of antibodies against MOG is the defining characteristic of MOG antibody disease (MOGAD), an inflammatory condition distinct from multiple sclerosis (MS), and is used as a key diagnostic biomarker.
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