NoGeneST™ PTP-1B-ASO, Antisense Oligonucleotide

Name: NoGeneST™ PTP-1B-ASO, Antisense Oligonucleotide
SKU: NRYF-0625-XY53
Rating: 5 (1 reviews)

[CAT#: NRYF-0625-XY53]

Target:: PTP-1B

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Product Overview

Description

PTP-1B-ASO is an antisense oligonucleotide that inhibits protein tyrosine phosphatase 1B (PTP-1B).

Species

Human

Applications

Modulates insulin/glucagon signaling in neurodegenerative diseases (e.g., Alzheimer's) by targeting PTP-1B, a negative regulator of insulin receptor phosphorylation. Enables investigation of PTP-1B's role in neuronal energy metabolism, amyloid-beta clearance, and synaptic plasticity. Ideal for in vitro (neuronal/glial cultures) and in vivo (diabetes/AD mouse models) studies.

Relevant Diseases

Obesity

Properties

Appearance

Solid

Shipping

Room temperature

Storage

Store at -20°C, sealed and away from moisture.
In solvent, store at -80°C for up to 6 months, or -20°C for up to 1 month (sealed and away from moisture).