Dextran, Azide Functional

Product Overview

Description

Dextrans are hydrophilic polysaccharides characterized by their moderate-to-high molecular weight (3-200 kD). These molecules can exist in either charged or uncharged forms depending on the conjugated fluorophore. Due to their low immunogenic properties, dextrans are often used as effective tracers in various applications.
Azide functionalized Dextrans are reactive toward alkyne or dibenzylcyclooctyne (DBCO) groups.

Tracer Type

Dextan Conjugate

Applications

Neural Tracing

Research Areas

Neural Circuit Mapping

Properites

Standard Filter Set

Dextran

Soluble In

Water

Appearance

Dried powder

Shipping

Blue ice

Storage

4-8 °C

Research Use Only

For research use only.

Publications

Publications (0)

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Case Studies

Customer Reviews and Q&As

Customer Reviews Average Customer Ratings Overall

5.0

Excellent

Excellent for neural tracing applications

Its high molecular weight and azide functionality allow for precise labeling and tracing of neural pathways. The product's solubility and stability are impressive, making it easy to work with in various experimental conditions.

Excellent

The product is consistent in quality and highly effective

We've used this Dextran for several neural tracing projects. The quality is consistently high, and its performance in conjugation reactions is excellent. It has significantly improved the accuracy of our tracing studies, providing clear and reliable results.

Excellent

We appreciate the detailed product specifications provided

It integrates well with our click chemistry protocols and has proven to be highly effective in our neural mapping studies. The product is well-packaged, and the delivery was prompt.

Excellent

It has consistently met our expectations

It provides consistent labeling and allows for precise tracking of neuronal connections. The reagent's purity and functional groups work well in our applications.

Excellent

It provides excellent signal clarity

It is easy to use and produces high-quality results every time. The 70,000 Da size is ideal for our experimental needs, and we have noticed significant improvements in our data accuracy.

Q&As

How long can the Dextran be stored after opening?

Once opened, the Dextran should be used within 6 months for optimal performance. Store it at -20°C and protect it from light and moisture. Always check for any signs of degradation or contamination before use to ensure reliable results.

Can this product be used in combination with other fluorescent or chromogenic markers?

Yes, the Dextran can be used in conjunction with other fluorescent or chromogenic markers. Its azide functionality allows for click chemistry reactions, which can be paired with various detection methods. Ensure compatibility of the markers with your experimental setup to avoid interference.

What is the best method for conjugating Dextran with other molecules?

The best method for conjugating Dextran is through click chemistry reactions, specifically using azide-alkyne cycloaddition. This method is highly efficient and provides strong, stable conjugation. Ensure that the alkyne-functionalized molecules you use are compatible with the azide group for effective conjugation.