Product Overview

Immunogen

Partial human cathepsin B recombinant protein (18-339 a.a.) expressed in E. coli.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP2183

Applications

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Handling Advice

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

Cathepsin B

Official Name

CTSB

Full Name

Cathepsin B

Alternative Names

CTSB; CPSB; APP secretase; APPS; Cathepsin B1

Gene ID

1508 (Human); 13030 (Mouse); 64529 (Rat)

Uniprot ID

P07858 (Human); P10605 (Mouse); P00787 (Rat)

References

1. Mohamed MM, Sloane BF. 2006. Nat. Rev. Cancer 6:764.
2. Wang C, et al. 2012. J. Biol. Chem. 47:39834.
3. Grzonka Z, et al. 2001. Acta Biochim. Pol. 48:1.
4. Liu J, et al. 2006. FEBS Letters 580:245.
5. Brix K, et al. 2008. Biochimie. 90:194.
6. Turk V, et al. 2012. Biochim. Biophys. Acta. 1824:68.

Publications