Product
Cathepsin B (CTSB) Inhibitor Screening Kit (Fluorometric), Human
[CAT#: NK1120FY058]
Only kit on the market to screen Cathepsin B inhibitors
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Overview
Description
Cathepsin B (CTSB, EC 3.4.22.1) is a lysosomal cysteine protease, which is recommended to participate in intracellular degradation and protein renewal. It is also related to tumor invasion and metastasis. Our cathepsin B inhibitor screening kit utilizes the ability of cathepsin B to cleave AFC-based synthetic peptide substrates to release AFC, which can be easily quantified using a fluorometer or fluorescence microplate reader. In the presence of cathepsin B-specific inhibitors, the cleavage of the substrate is reduced/eliminated, resulting in a reduction or complete loss of AFC fluorescence. This simple and high-throughput adaptability assay kit can be used to screen/research/characterize potential inhibitors of cathepsin B.
Screen/study/characterize potential inhibitors of Cathepsin B.
Screen/study/characterize potential inhibitors of Cathepsin B.
Species Reactivity
Human
Relevant Diseases
Neurological Disorders
Properites
Detection Method
Fluorescence (Ex/Em = 400/505 nm)
Assay Type
ELISA kit
Components
• CTSB Reaction Buffer
• CTSB Reagent
• Cathepsin B (human)
• CTSB Substrate, Ac-RR-AFC (10 mM)
• CTSB Inhibitor (F-F-FMK, 1 mM)
• CTSB Reagent
• Cathepsin B (human)
• CTSB Substrate, Ac-RR-AFC (10 mM)
• CTSB Inhibitor (F-F-FMK, 1 mM)
Preparation and Storage
Shipping
Gel Pack
Storage
-20°C
Research Use Only
For research use only
Target Details
Publications
Publications (0)
Neural Antibodies
Kits
For Research Use Only. Not For Clinical Use.
