Product
Mouse Anti-SHANK1 Monoclonal Antibody (CBP2358)
[CAT#: NAB2010358LS]
Anti-SHANK1 Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat
- Applications:
- WB; IHC-P; ICC
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
SHANK proteins are adapter proteins that are mainly localized to the post-synaptic densities of excitatory synapses. SHANK interacts with other post-synaptic density proteins such as PSD-95 and Homer to form a complex structure, which anchors glutamate receptors to the post-synaptic membrane.
Immunogen
Fusion protein corresponding to amino acids 84-309 (SH3/PDZ domains) of rat Shank2
Species Reactivity
Human; Mouse; Rat
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1, κ
Clone Number
CBP2358
Applications
WB; IHC-P; ICC
Application Notes
WB (1.0-5 µg/mL); IHC-P (5.0-10 µg/mL)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide.
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Handling Advice
Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Target
SHANK1
Official Name
SHANK1
Full Name
SH3 And Multiple Ankyrin Repeat Domains 1
Alternative Names
SH3 And Multiple Ankyrin Repeat Domains 1; Somatostatin Receptor-Interacting Protein; SSTR-Interacting Protein; SSTRIP; SH3 And Multiple Ankyrin Repeat Domains Protein 1; SPANK-1; Synamon; Shank1;
References
1.Monteiro P, et al. 2017. Nat Rev Neurosci. 18(3):147
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
