Mouse Anti-SHANK1 Monoclonal Antibody (CBP2358)

Product Overview

Description

SHANK proteins are adapter proteins that are mainly localized to the post-synaptic densities of excitatory synapses. SHANK interacts with other post-synaptic density proteins such as PSD-95 and Homer to form a complex structure, which anchors glutamate receptors to the post-synaptic membrane.

Immunogen

Fusion protein corresponding to amino acids 84-309 (SH3/PDZ domains) of rat Shank2

Species Reactivity

Human; Mouse; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP2358

Applications

WB; IHC-P; ICC

Application Notes

WB (1.0-5 µg/mL); IHC-P (5.0-10 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Handling Advice

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

SHANK1

Official Name

SHANK1

Full Name

SH3 And Multiple Ankyrin Repeat Domains 1

Alternative Names

SH3 And Multiple Ankyrin Repeat Domains 1; Somatostatin Receptor-Interacting Protein; SSTR-Interacting Protein; SSTRIP; SH3 And Multiple Ankyrin Repeat Domains Protein 1; SPANK-1; Synamon; Shank1;