Product
Mouse Anti-Glutamine synthetase Monoclonal Antibody (CBP2376)
[CAT#: NAB2010395LS]
Anti-Glutamine synthetase Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human; Rat
- Applications:
- WB; IHC-P; ICC
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Glutamine Synthase (GLUL) is primarily expressed in astrocytes in the brain. The main function of GLUL is to catalyze the condensation of glutamate and ammonia to form glutamine. GLUL plays an important role in the metabolic regulation of glutamate, detoxification of brain ammonia, as well as recycling of neurotransmitters. GLUL expression in endothelial cells may be involved in cell migration during pathological angiogenesis. Upregulation of astrocytic GLUL to uptake excess ammonia and glutamate may play a neuroprotective role during neuroinflammation.
Immunogen
Recombinant human GLUL protein expressed in HEK293T cell
Species Reactivity
Human; Rat
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG2a, κ
Clone Number
CBP2376
Applications
WB; IHC-P; ICC
Application Notes
WB (1.0-10 µg/mL)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide.
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Handling Advice
Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Target
Glutamine synthetase
Official Name
Glutamine synthetase
Full Name
Glutamine synthetase
Alternative Names
GLUL; Glutamine Synthetase
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
