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NeuroMab™ Rat Anti-Trem-2 Monoclonal Antibody (CBP2550)
[CAT#: NAB2007FY940]
Rat Monoclonal [NS78.18] to Trem-2
- Host Species:
- Rat
- Species Reactivity:
- Mouse
- Applications:
- FC
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
The rat anti-Mouse TREM-2 antibody, recognizes the trigger receptor expressed on myeloid cell 2 (TREM-2), an activating receptor of the Ig superfamily. TREM-2 and DAP12 form a receptor signaling complex to trigger the activation of immune responses in macrophages and dendritic cells. It may be related to chronic inflammation and may promote the production of constitutive rather than inflammatory chemokines and cytokines. TREM-2 may also have a functional role in the formation of osteoclasts.
Immunogen
Mouse TREM-2 Fc Fusion Protein.
Species Reactivity
Mouse
Clonality
Monoclonal
Host Species
Rat
Isotype
IgG1
Clone Number
CBP2550
Applications
FC
Application Notes
FC: 1/25-1/200
Relevant Diseases
Amyotrophic Lateral Sclerosis; Frontotemporal Dementia
Conjugation
Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1859
Product Properties
Form
Liquid
Formulation
PBS, 0.09% Sodium Azide
Preservatives
YES
Concentration
1 mg/ml
Purification
Protein G
Endotoxin Level
Low Endotoxin
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend micr°Centrifugation before use.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Target
TREM2
Official Name
TREM2
Full Name
TREM2 Gene(Protein Coding) Triggering Receptor Expressed On Myeloid Cells 2
Alternative Names
Triggering Receptor Expressed On Myeloid Cells 2; Triggering Receptor Expressed On Myeloid Cells 2a; Triggering Receptor Expressed On Monocytes 2; TREM-2; Trem2a; Trem2b; Trem2c;
References
1. Humphrey, M.B. et al. (2006) TREM2, a DAP12-associated receptor, regulates osteoclast differentiation and function.
Publications
Publications (0)
Neural Cell Lines
Neural Antibodies
For Research Use Only. Not For Clinical Use.
