Mouse Anti-BCL2 Monoclonal Antibody (CBP2628)

Product Overview

Description

Bcl-2 (B-cell lymphoma 2) is an outer mitochondrial membrane protein that via heterodimerization with BAX proteins controls apoptosis. Abnormalities of Bcl-2 activity can lead to cancer, autoimmune diseases, and schizophrenia.

Expression Host

Mammalian cells

Immunogen

BCL2 fusion protein Ag3508

Species Reactivity

Human; Porcine

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2b

Clone Number

CBP2628

Applications

FC; IF; IHC; IP; WB; ELISA

Application Notes

IF : 1:20-1:200; IHC : 1:20-1:200; IP : 0.5-4.0 ug; WB : 1:500-1:1000

Research Areas

Metabolism

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

1000 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

Bcl-2

Official Name

BCL2

Full Name

B-cell CLL/lymphoma 2

Alternative Names

Apoptosis regulator Bcl 2; B cell CLL/lymphoma 2; BCL2; BCL-2; Oncogene B cell leukemia 2

Gene ID

596(Human)

Uniprot ID

P10415(Human)

References

1. Li, L., Liu, M., Zhang, Z., Zhang, W., Liu, N., Sheng, X., & Wei, P. (2019). Derlin1 functions as an oncogene in cervical cancer via AKT/mTOR signaling pathway. Biological research, 52. 2. Shi, H., Yao, R., Lian, S., Liu, P., Liu, Y., Yang, Y. Y.,... & Li, S. (2019). Regulating glycolysis, the TLR4 signal pathway and expression of RBM3 in mouse liver in response to acute cold exposure. Stress, 22(3), 366-376. 3. Li, K., Meng, Z., Jiang, L., Xia, C., Xu, K., Yuan, D.,... & Liu, S. (2019). CDKL1 promotes the chemoresistance of human oral squamous cell carcinoma cells to hydroxycamptothecin. Molecular and cellular probes, 44, 57-62.

Publications