Mouse Anti-GFAP Monoclonal Antibody (CBP2635)

Product Overview

Description

GFAP (Glial fibrillary acidic protein) is a type III intermediate filament (IF) protein specific to the central nervous system (CNS). GFAP is one of the main components of the intermediate filament network in astrocytes and has been proposed as playing a role in cell migration, cell motility, maintaining mechanical strength, and in mitosis.

Expression Host

Mammalian cells

Immunogen

GFAP fusion protein Ag10452

Species Reactivity

Human; Mouse; Rat; Porcine; Rabbit

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2a

Clone Number

CBP2635

Applications

IHC; IP; WB; ELISA

Application Notes

IHC : 1:20-1:200; IP : 0.5-4.0 ug; WB : 1:500-1:1000

Research Areas

GPCR

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

1500 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

GFAP

Official Name

GFAP

Full Name

Glial fibrillary acidic protein

Alternative Names

GFAP

Gene ID

14580(Human); 24387(Mouse)

Uniprot ID

P03995(Mouse); P47819(Rat)

References

1. Fan, J., Chen, M., Wang, X., Tian, Z., Wang, J., Fan, D.,... & Dai, X. (2019). Targeting Smox is neuroprotective and ameliorates brain inflammation in cerebral ischemia/reperfusion rats. Toxicological Sciences, 168(2), 381-393. 2. Resistin-Inhibited Neural Stem Cell-Derived Astrocyte Differentiation Contributes to Permeability Destruction of the Blood-Brain Barrier. 3. Dong, W., Sun, Y., Cheng, H., Yang, B., Wang, L., Jiang, Z.,... & Zhao, R. (2019). Dynamic cell type-specific expression of Nrf2 after traumatic brain injury in mice. European Journal of Neuroscience, 50(2), 1981-1993.

Publications