Mouse Anti-NES Monoclonal Antibody (CBP2729)

Product Overview

Description

Nestin is a class VI intermediate filament protein expressed in stem cells of the central nervous system (CNS) but not in mature CNS cells. Its expression is used extensively as a marker for neural lineage cells derived from human embryonic stem (hES) and induced pluripotent stem (iPS) cells. Nestin is also expressed in non-neural stem cell populations such as pancreatic islet progenitors and hematopoietic progenitors.

Expression Host

Mammalian cells

Immunogen

Peptide

Species Reactivity

Human; Mouse; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2b

Clone Number

CBP2729

Applications

WB; ELISA

Application Notes

WB : 1:500-1:1000

Research Areas

GPCR

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

1373 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

NES

Official Name

NES

Full Name

Nestin

Alternative Names

NES; Nestin

Gene ID

10763(Human)

Uniprot ID

P48681(Human)

References

1. Fan, Y., Xue, W., Schachner, M., & Zhao, W. (2019). Honokiol eliminates glioma/glioblastoma stem cell-like cells via JAK-STAT3 signaling and inhibits tumor progression by targeting epidermal growth factor receptor. Cancers, 11(1), 22. 2. Mu, T., Qin, Y., Liu, B., He, X., Liao, Y., Sun, J.,... & Cai, J. (2018). In vitro neural differentiation of bone marrow mesenchymal stem cells carrying the FTH1 reporter gene and detection with MRI. BioMed research international, 2018. 3. Ke, X., Do, D. C., Li, C., Zhao, Y., Kollarik, M., Fu, Q.,... & Gao, P. (2019). Ras homolog family member A/Rho-associated protein kinase 1 signaling modulates lineage commitment of mesenchymal stem cells in asthmatic patients through lymphoid enhancer-binding factor 1. Journal of Allergy and Clinical Immunology, 143(4), 1560-1574.

Publications